منابع مشابه
Helicobacter breaks down junctions
and colleagues. Although the bacteria may do it to gain access to tasty chemicals that leak out, the results for humans may include stomach ulcers and gastric cancer. The link from cell junctions to stomach ailments may, say the researchers, lie in tissue repair. Injury to the stomach triggers cell division and migration to plug the gap. The chiefs in charge of these processes may well lie in c...
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A droplet deposited or impacting on a superhydrophobic surface rolls off easily, leaving the surface dry and clean. This remarkable property is due to a surface structure that favors the entrainment of air cushions beneath the drop, leading to the so-called Cassie state. The Cassie state competes with the Wenzel (impaled) state, in which the liquid fully wets the substrate. To use superhydropho...
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The spontaneous development of destructive polyarthritis in mice transgenic for an autoreactive T-cell receptor supports the notion that a failure of T-cell self-tolerance can lead to similar diseases in humans, and sheds new light on the role of peripheral tolerance in the avoidance of such pathological immune responses.
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Objective(s): Chemoresistance remains the main causes of treatment failure and mortality in cancer patients. There is an urgent need to investigate novel approaches to improve current therapeutic modalities and increase cancer patients' survival. Induction of drug efflux due to overexpression of P-glycoproteins is considered as an important leading cause of multidrug resistance...
متن کاملThe chips are down for Helicobacter pylori.
T he whole genome sequence of Helicobacter pylori strain 26695 was published in 1997 and that of a second strain, J99, in 1999. 2 These publications moved H pylori research forward by a quantum leap. Comparing H pylori genes with genes of known function in other bacteria gave immediate insights into H pylori metabolism, structure, adaptive mechanisms, and virulence. Research became more focused...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2003
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb1616rr3